TNP o TPAN
نویسندگان
چکیده
Muchos esfuerzos internacionales han sido destinados a los propósitos de controlar, reducir y prohibir las armas nucleares. Mientras que el actual orden nuclear orbita en torno al Tratado sobre la No Proliferación Armas Nucleares (TNP), aquellos más desconfiados sostenibilidad disuasión defienden instaurar un régimen desarme universal basado Prohibición (TPAN). En seno Unión Europea (UE) existe una disparidad posiciones ese respecto, tanto entre órganos como Estados miembros, lo dificulta adopción estrategia coherente. Abordando impacto cuestiones relevantes guerra Ucrania nuclear-sharing, artículo esboza tesitura se encuentra UE relación con Se repasa evolución su rol actor emergente teatro europeo, describen principales modelos posible analizan desafíos enfrenta conjuntamente marco vigente; endógenos (la divergencia miembros) exógenos (los riesgos derivados proliferación Irán). El argumenta que, para mantener no facilitar desnuclearización universal, debería afrontar urgencia retos descritos contribuir reforzar TNP.
منابع مشابه
In Vitro Induction of Cytotoxicity of C 57 BL / IO Spleen Cells by TNP - Modified or TNP - A GG - Modified Spleen Cells to TNP - Modified and TNP - A GG
At least four different assays have been used to investigate the fine specificity of lymphocytes considered to possess T-cell characteristics. These methods include delayed hypersensitivity reactions in guinea pigs (1-4), in vitro proliferation of peritoneal lymphocytes in guinea pigs (3, 4) and mice (5), macrophage migration inhibition by lymphocytes (4), and the generation of cytotoxic T lymp...
متن کاملOptimizing the dosing schedule of TNP-470 [O-(chloroacetyl-carbamoyl) fumagillol] enhances its antitumor and antiangiogenic efficacies.
Many drugs vary in potency and/or toxicity according to the time of day when they are administered. In this study, we investigated whether antitumor efficacy of angiogenesis inhibitor, TNP-470 [O-(chloroacetyl-carbamoyl) fumagillol], could be improved by optimizing the dosing schedule. Tumor-bearing mice were housed under standardized light/dark cycle conditions (lights on at 7:00 AM, off at 7:...
متن کاملTNP-470 is an effective antimicrosporidial agent.
Therapy for microsporidia, which cause diarrhea and a wasting syndrome in persons with AIDS, has had limited success. Fumagillin, a naturally secreted water-insoluble antibiotic, has in vitro activity against microsporidia and has been used successfully in the treatment of superficial keratitis in patients with AIDS, but systemic therapy has been limited by toxicity of the currently available f...
متن کاملCompetitive antagonism of recombinant P2X(2/3) receptors by 2', 3'-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP).
TNP-ATP has become widely recognized as a potent and selective P2X receptor antagonist, and is currently being used to discriminate between subtypes of P2X receptors in a variety of tissues. We have investigated the ability of TNP-ATP to inhibit alpha,beta-methylene ATP (alpha,beta-meATP)-evoked responses in 1321N1 human astrocytoma cells expressing recombinant rat or human P2X(2/3) receptors. ...
متن کاملAnterior chamber associated immune deviation induced by TNP-splenocytes (TNP-ACAID). I. Systemic tolerance mediated by suppressor T-cells.
The relationship between the anterior chamber (AC) of the eye and the immune system was studied after intracameral inoculation with the hapten TNP. Injection of syngeneic TNP-modified splenocytes (TNP-Sp) into the AC of Balb/c mice results in suppressed systemic cell-mediated immunity to TNP as determined by the ear swelling assay. This aberrant immune responsiveness following AC injection of T...
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ژورنال
عنوان ژورنال: Ana?lisis Juri?dico - Poli?tico
سال: 2023
ISSN: ['2665-5489', '2665-5470']
DOI: https://doi.org/10.22490/26655489.6557